منابع مشابه
Genetic Markers Used for Risk Stratification in Multiple Myeloma
While no specific genetic markers are required in the diagnosis of multiple myeloma (MM), multiple genetic abnormalities and gene signatures are used in disease prognostication and risk stratification. This is particularly important for the adequate identification of the high-risk MM group, which does not benefit from any of the current therapies, and novel approaches need to be proposed. Fluor...
متن کاملGenetic Stratification to Identify Risk Groups for Alzheimer’s Disease
Stratification by genetic risk factors for Alzheimer's disease (AD) may help identify groups with the greatest disease risk. Biological changes that cause late-onset AD are likely to occur years, if not decades prior to diagnosis. Here, we select a subset of the Generation Scotland: Scottish Family Health Study cohort in a likely preclinical age-range of 60-70 years (subset n = 3,495 with cogni...
متن کاملStrongly enhanced colorectal cancer risk stratification by combining family history and genetic risk score
Background and aim Family history (FH) and genetic risk scores (GRSs) are increasingly used for risk stratification for colorectal cancer (CRC) screening. However, they were mostly considered alternatively rather than jointly. The aim of this study was to assess the potential of individual and joint risk stratification for CRC by FH and GRS. Patients and methods A GRS was built based on the n...
متن کاملRisk stratification, risk adjustment, and other risks.
“BUT our patients are sicker than yours!” is the refrain when physicians are faced with adverse comparisons of their patients’ outcomes with those of other groups, hospitals, or health systems. Meaningful and fair comparison of clinical performance requires statistical adjustment of outcomes for differences in clinical acuity of patients treated and complexity of procedures performed, among oth...
متن کاملRisk stratification in Brugada syndrome.
Kathryn A Glatter*, Nipavan Chiamvimonvat, Matti Viitasalo, Qing Wang, and Dipika Tuteja Department of Cardiology,University of California, Davis, Sacramento, CA 95817, USA (KAG, NC, DT); Department of Cardiology,Helsinki University Hospital, Helsinki, Finland (MV); and Center for Cardiovascular Genetics and Department of Molecular Cardiology Cardiology, Cleveland Clinic Foundation, Cleveland, ...
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ژورنال
عنوان ژورنال: JACC: Basic to Translational Science
سال: 2021
ISSN: 2452-302X
DOI: 10.1016/j.jacbts.2020.09.004